This week we will focus on using a CAT to critique three articles. Here is what to do: 1) Find three articles that are central to your EBP practice project. You can use the same ones or three different ones from previous weeks-your choice. HINT: Pick articles that are randomized control trials. These are usually more straight forward. 2) Goto the CAT website above and select a tool THAT SPECIFICALLY is designed to critique the type of articles you have. HINT: Usually goes by type of research method design (i.e. Randomized Control Trial, qualitative, etc). 3) Use the CAT tool as a general guide, provide a critique of the articles. 4) Attach your critique in APA format with Title and Reference Pages (NO MORE THAN 3 pages FOR ALL THREE ARTICLES, not including title page and reference page.) HINT: Hang on to these, as they will form the groundwork for your critique assignment. 5) When others have posted, critique each others critique and APA format and make recommendations on corrections. 6) POST ON THE MAIN DISCUSSION BOARDNOT IN YOUR GROUPS. This week we will focus on using a CAT to critique three articles. Here is what to do: 1) Find three articles that are central to your EBP practice project. You can use the same ones or three different ones from previous weeks-your choice. HINT: Pick articles that are randomized control trials. These are usually more straight forward. 2) Goto the CAT website above and select a tool THAT SPECIFICALLY is designed to critique the type of articles you have. HINT: Usually goes by type of research method design (i.e. Randomized Control Trial, qualitative, etc). 3) Use the CAT tool as a general guide, provide a critique of the articles. 4) Attach your critique in APA format with Title and Reference Pages (NO MORE THAN 3 pages FOR ALL THREE ARTICLES, not including title page and reference page.) HINT: Hang on to these, as they will form the groundwork for your critique assignment. 5) When others have posted, critique each others critique and APA format and make recommendations on corrections. 6) POST ON THE MAIN DISCUSSION BOARDNOT IN YOUR GROUPS. ARTICLE 1 Title: Comparing the effectiveness of vitamin b6 and ginger in treatment of pregnancy-induced nausea and vomiting. Authors: Haji Seid Javadi E; Department of Obstetrics and Gynecology, Qazvin University of Medical Sciences, Qazvin, Iran. Salehi F Mashrabi O Source: Obstetrics And Gynecology International [Obstet Gynecol Int] 2013; Vol. 2013, pp. 927834. Date of Electronic Publication: 2013 Oct 22. Publication Type: Journal Article Language: English Journal Info: Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 101517078 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1687-9589 (Print) NLM ISO Abbreviation: Obstet Gynecol Int Subsets: PubMed not MEDLINE Imprint Name(s): Original Publication: [New York, NY] : Hindawi Pub. Corp. Abstract: Objective. Comparing the effectiveness of vitamin B6 (40 mg twice daily) and ginger (250 mg four times daily) in treatment of pregnancy nausea. Methods. In a clinical trial in health centers of Qazvin University of Medical Sciences from November 2010 to February 2011 on pregnant mothers, the effects of vitamin B6 (40 mg twice daily) and ginger (250 mg four times daily) were evaluated in treatment of pregnancy nausea. Results. In both groups, treatments with vitamin B6 or ginger led to significant reduction in MPUQE score. Scores of symptoms at the day before treatment in vitamin B6 and ginger groups were 9.35 ¤ 1.97 and 9.80 ¤ 2.03, respectively, and reduced to 5.98 ¤ 1.45 and 6.28 ¤ 1.63, respectively, in the fourth day of treatment; however, mean changes in the two groups were not significantly different. Mean changes of MPUQE score in ginger and vitamin B6 groups were 8.32 ¤ 2.19 and 7.77 ¤ 1.80, respectively, showing no significant difference (P = 0.172). Conclusion. Vomiting was more reduced in vitamin B6 group; however, this reduction was not statistically significant. There was no significant difference between the two groups in nausea occurrences and their duration. No side effect was observed in either group. Entry Date(s): Date Created: 20131119 Date Completed: 20131119 Latest Revision: 20131122 Update Code: 20131212 PubMed Central ID: PMC3819920 DOI: 10.1155/2013/927834 PMID: 24250336 Database: MEDLINE Full Text Database: Academic Search Complete Result List Refine Search t ARTICLE 2 Title: A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting. Authors: Viljoen, Estelle1,2 estelleviljoen00@gmail.com Visser, Janicke1 jconrad@sun.ac.za Koen, Nelene1 nelene@sun.ac.za Musekiwa, Alfred3 alfred.musekiwa@gmail.com Abstract: Background and objectives Nausea and vomiting during pregnancy (NVP) occur commonly. Possible harmful side-effects of conventional medicine to the fetus create the need for alternative options to relieve NVP. This systematic review (SR) investigated current evidence regarding orally administered ginger for the treatment of NVP. The primary objective was to assess the effectiveness of ginger in treating NVP. The secondary objective was to assess the safety of ginger during pregnancy. Methods A comprehensive electronic bibliographic database search was carried out. Randomized controlled trials (RCTs) of the efficacy of orally administered ginger, as treatment for NVP in pregnant women at any stage of pregnancy, published in English, were included. Two researchers independently extracted data and assessed trial quality. RevMan5 software (Cochrane Collaboration) was used for data analysis. p < 0.05 was considered statistically significant. Results Twelve RCTs involving 1278 pregnant women were included. Ginger significantly improved the symptoms of nausea when compared to placebo (MD 1.20, 95% CI 0.56-1.84, p = 0.0002, I? = 0%). Ginger did not significantly reduce the number of vomiting episodes during NVP, when compared to placebo, although there was a trend towards improvement (MD 0.72, 95% CI -0.03-1.46, p = 0.06, I? = 71%). Subgroup analyses seemed to favor the lower daily dosage of <1500 mg ginger for nausea relief. Ginger did not pose a significant risk for spontaneous abortion compared to placebo (RR 3.14, 95% CI 0.65-15.11, p = 0.15; I? = 0%), or to vitamin B6 (RR 0.49, 95% CI 0.17-1.42, p = 0.19, I? = 40%). Similarly, ginger did not pose a significant risk for the side-effects of heartburn or drowsiness. Conclusions This review suggests potential benefits of ginger in reducing nausea symptoms in pregnancy (bearing in mind the limited number of studies, variable outcome reporting and low quality of evidence). Ginger did not significantly affect vomiting episodes, nor pose a risk for side-effects or adverse events during pregnancy. Based on evidence from this SR, ginger could be considered a harmless and possibly effective alternative option for women suffering from NVP. International Prospective Register of Systematic Reviews (PROSPERO) registration number: CRD42011001237. [ABSTRACT FROM AUTHOR] ARTICLE 1 Title: Comparing the effectiveness of vitamin b6 and ginger in treatment of pregnancy-induced nausea and vomiting. Authors: Haji Seid Javadi E; Department of Obstetrics and Gynecology, Qazvin University of Medical Sciences, Qazvin, Iran. Salehi F Mashrabi O Source: Obstetrics And Gynecology International [Obstet Gynecol Int] 2013; Vol. 2013, pp. 927834. Date of Electronic Publication: 2013 Oct 22. Publication Type: Journal Article Language: English Journal Info: Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 101517078 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1687-9589 (Print) NLM ISO Abbreviation: Obstet Gynecol Int Subsets: PubMed not MEDLINE Imprint Name(s): Original Publication: [New York, NY] : Hindawi Pub. Corp. Abstract: Objective. Comparing the effectiveness of vitamin B6 (40 mg twice daily) and ginger (250 mg four times daily) in treatment of pregnancy nausea. Methods. In a clinical trial in health centers of Qazvin University of Medical Sciences from November 2010 to February 2011 on pregnant mothers, the effects of vitamin B6 (40 mg twice daily) and ginger (250 mg four times daily) were evaluated in treatment of pregnancy nausea. Results. In both groups, treatments with vitamin B6 or ginger led to significant reduction in MPUQE score. Scores of symptoms at the day before treatment in vitamin B6 and ginger groups were 9.35 ¤ 1.97 and 9.80 ¤ 2.03, respectively, and reduced to 5.98 ¤ 1.45 and 6.28 ¤ 1.63, respectively, in the fourth day of treatment; however, mean changes in the two groups were not significantly different. Mean changes of MPUQE score in ginger and vitamin B6 groups were 8.32 ¤ 2.19 and 7.77 ¤ 1.80, respectively, showing no significant difference (P = 0.172). Conclusion. Vomiting was more reduced in vitamin B6 group; however, this reduction was not statistically significant. There was no significant difference between the two groups in nausea occurrences and their duration. No side effect was observed in either group. Entry Date(s): Date Created: 20131119 Date Completed: 20131119 Latest Revision: 20131122 Update Code: 20131212 PubMed Central ID: PMC3819920 DOI: 10.1155/2013/927834 PMID: 24250336 Database: MEDLINE Full Text Database: Academic Search Complete Result List Refine Search t ARTICLE 2 Title: A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting. Authors: Viljoen, Estelle1,2 estelleviljoen00@gmail.com Visser, Janicke1 jconrad@sun.ac.za Koen, Nelene1 nelene@sun.ac.za Musekiwa, Alfred3 alfred.musekiwa@gmail.com Abstract: Background and objectives Nausea and vomiting during pregnancy (NVP) occur commonly. Possible harmful side-effects of conventional medicine to the fetus create the need for alternative options to relieve NVP. This systematic review (SR) investigated current evidence regarding orally administered ginger for the treatment of NVP. The primary objective was to assess the effectiveness of ginger in treating NVP. The secondary objective was to assess the safety of ginger during pregnancy. Methods A comprehensive electronic bibliographic database search was carried out. Randomized controlled trials (RCTs) of the efficacy of orally administered ginger, as treatment for NVP in pregnant women at any stage of pregnancy, published in English, were included. Two researchers independently extracted data and assessed trial quality. RevMan5 software (Cochrane Collaboration) was used for data analysis. p < 0.05 was considered statistically significant. Results Twelve RCTs involving 1278 pregnant women were included. Ginger significantly improved the symptoms of nausea when compared to placebo (MD 1.20, 95% CI 0.56-1.84, p = 0.0002, I? = 0%). Ginger did not significantly reduce the number of vomiting episodes during NVP, when compared to placebo, although there was a trend towards improvement (MD 0.72, 95% CI -0.03-1.46, p = 0.06, I? = 71%). Subgroup analyses seemed to favor the lower daily dosage of <1500 mg ginger for nausea relief. Ginger did not pose a significant risk for spontaneous abortion compared to placebo (RR 3.14, 95% CI 0.65-15.11, p = 0.15; I? = 0%), or to vitamin B6 (RR 0.49, 95% CI 0.17-1.42, p = 0.19, I? = 40%). Similarly, ginger did not pose a significant risk for the side-effects of heartburn or drowsiness. Conclusions This review suggests potential benefits of ginger in reducing nausea symptoms in pregnancy (bearing in mind the limited number of studies, variable outcome reporting and low quality of evidence). Ginger did not significantly affect vomiting episodes, nor pose a risk for side-effects or adverse events during pregnancy. Based on evidence from this SR, ginger could be considered a harmless and possibly effective alternative option for women suffering from NVP. International Prospective Register of Systematic Reviews (PROSPERO) registration number: CRD42011001237. [ABSTRACT FROM AUTHOR]
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